Candidate: Anti-SARS-CoV-2 monoclonal antibodies for the treatment of COVID-19 Types: Fully human monoclonal antibodies targeting immutable sites confirmed as 98.71% to 99.29% conserved over the entirety of all 1 million coronavirus isolates. Enzolytics says it has confirmed that the analyzed sites are conserved sites not only on the initial virus strains but also existing in the Delta and Lambda variants, as well […]
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A new study published in Nature Communications reconstructs regional incidence profiles of COVID-19, highlighting the effects of non-pharmaceutical interventions (NPI) and different testing strategies. Daily counts of new COVID-19 cases remain a basis for evaluating the state of the pandemic and are vital for making informed decisions on public interventions. These case counts, however, are based on positive diagnostic test results and are […]
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Study is the first to demonstrate cross-protective immunity by vaccines. Northwestern Medicine scientists have shown for the first time that coronavirus vaccines and prior coronavirus infections can provide broad immunity against other, similar coronaviruses. The findings build a rationale for universal coronavirus vaccines that could prove useful in the face of future epidemics. “Until our study, what hasn’t been clear […]
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Strong antibody response to mRNA vaccines declined over an eight-month follow-up period; lower initial response to single-shot Ad26 vaccine remained stable over time, research shows. Based on the strength of clinical trial data showing the vaccines conferred robust protection against COVID-19, the U.S. Food & Drug Administration granted emergency use authorization to the mRNA-based vaccines known as BNT162b2 (BioNTech, Pfizer) and mRNA-1273 (Moderna) in December 2020, and to the Ad26.COV2.S (Johnson […]
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People who had received a first dose of the Oxford-AstraZeneca COVID-19 vaccine and received an mRNA vaccine for their second dose had a lower risk of infection compared to people who had received both doses of the Oxford-AstraZeneca vaccine. This is shown in a nationwide study performed by researchers at Umeå University, Sweden. “Having received any of the approved vaccines is better […]
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A clinical trial has found that treatment with the immunomodulator interferon beta-1a plus the antiviral remdesivir was not superior to treatment with remdesivir alone in hospitalized adults with COVID-19 pneumonia. In addition, in a subgroup of patients who required high-flow oxygen, investigators found that interferon beta-1a was associated with more adverse events and worse outcomes. These findings were published today (October 18, […]
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Valneva vaccine shows good outcomes in comparison with AstraZeneca jab A covid-19 vaccine made by Valneva produced stronger antibody responses and fewer side effects than the Oxford/AstraZeneca vaccine in a clinical trial, the French company has announced. The trial included more than 4600 participants in the UK, who were randomly allocated one of the two vaccines, while delta was the predominant […]
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A team of researchers has developed a new nanomechanical technique for fast, one-step, immune-affinity tests, which can quantify the immune response induced by different COVID-19 variants in serum. Their technique provides a new tool for tracking infection immunity over time and for analysing new vaccine candidates. Led by Professor Martin Hegner, Principal Investigator in the Trinity Centre for Research on […]
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The incredible stress parents experienced during the COVID-19 pandemic had a negative effect on the eating habits of their children, according to a new study by researchers at the University of Houston College of Education. When stay-at-home mandates were ordered and school went virtual at the onset of the pandemic, many parents suddenly had to juggle multiple roles such as […]
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High BMI independently associated with death and longer ICU stay for COVID patients. Obese patients (BMI >35 kg/m2) were twice as likely to experience a prolonged ICU stay or die, in a large Swedish cohort study. In patients with COVID-19, a high body mass index (BMI) is associated with an increased risk of death and prolonged intensive care unit (ICU) stay, […]
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